CREM CLIA Kit for Human(Homo sapiens) | EIAab.comCREM CLIA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > CREM(Gene name) > Human

CREM (Gene name),

cAMP-responsive element modulator (Protein name ), CREM_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

CREM;

Protein name:

cAMP-responsive element modulator;

Alternative:

Inducible cAMP early repressor(ICER);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds DNA as a dimer. Interacts with FHL5 (By similarity). Interacts with CDC34.

Function:

Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

361

Sequence:

50:

100:

150:

200:

250:

300:

350:

361:

LKDICSPKTD | Y

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

Q03060

KEGG:

hsa:1390

Pfam:

PF00170

UniGene:

Hs.200250

SMR:

Q03060

MIM:

123812

Uniprot:

Q03060

FOR

ELISA Kit for Human cAMP-responsive element modulator

Cat.:

E15147h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human cAMP-responsive element modulator

Cat.:

E15147m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human cAMP-responsive element modulator

Cat.:

E15147r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human cAMP-responsive element modulator

Cat.:

E15147d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human cAMP-responsive element modulator

Cat.:

E15147b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human cAMP-responsive element modulator

Cat.:

U15147h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human cAMP-responsive element modulator

Cat.:

U15147r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human cAMP-responsive element modulator

Cat.:

U15147m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human cAMP-responsive element modulator

Cat.:

U15147b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human cAMP-responsive element modulator

Cat.:

U15147d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human cAMP-responsive element modulator

Cat.:

P15147Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human cAMP-responsive element modulator

Cat.:

P15147Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human cAMP-responsive element modulator

Cat.:

P15147Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human cAMP-responsive element modulator

Protein for Human cAMP-responsive element modulator

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Novel isoforms of human cyclic AMP-responsive element modulator (hCREM) mRNA."
Fujimoto T. , Fujisawa J. , Yoshida M.
J. Biochem.115:298-303(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 6; 7; 8; 9 AND 23)
2.

"cAMP inducibility of transcriptional repressor ICER in developing and mature human T lymphocytes."
Bodor J. , Spetz A.L. , Strominger J.L. , Habener J.F.
Proc. Natl. Acad. Sci. U.S.A.93:3536-3541(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 8);ALTERNATIVE SPLICING (ISOFORMS 6; 7 AND 9);VARIANT ARG-270
3.

"Human ICER1, a predicted alternative splice form of CREM, is evident in JEG-3 cells."
Brodie C.R. , Boland L.M. , Orr H.T.
Submitted (1998-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6)
4.

"The function of an isoform of hCREM gene in testis development."
Lu L. , Huang X.Y. , Xu M. , Xu Z.Y. , Li J.M. , Zhou Z.M. , Sha J.H.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5)
tissue: Testis.
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 5; 7; 20 AND 21)
tissue: Adrenal gland.
tissue: Heart.
tissue: Placenta.
tissue: Testis.
6.

"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 5 AND 22)
tissue: Brain.
tissue: Testis.
tissue: Uterus.
8.

"Searching for mutations in the human cAMP responsive element modulator (CREM) gene."
Vouk K. , Lalli E. , Scherer S.W. , Sassone-Corsi P. , Debeljak N. , Komel R. , Rozman D.
Submitted (2000-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-248
9.

"Novel leader exons of the cyclic adenosine 3',5'-monophosphate response element modulator (CREM) gene, transcribed from promoters P3 and P4, are highly testis-specific in primates."
Gellersen B. , Kempf R. , Sandhowe R. , Weinbauer G.F. , Behr R.
Mol. Hum. Reprod.8:965-976(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-26 (ISOFORM 10);ALTERNATIVE SPLICING (ISOFORMS 5; 10; 11 AND 12)
10.

"Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript."
Masquilier D. , Foulkes N.S. , Mattei M.-G. , Sassone-Corsi P.
Cell Growth Differ.4:931-937(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 17-361 (ISOFORMS 2 AND 3)
11.

"Cyclic AMP response element binding protein CREB and modulator protein CREM are products of distinct genes."
Meyer T.E. , Habener J.F.
Nucleic Acids Res.20:6106-6106(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 17-360 (ISOFORM 4)
tissue: Placenta.
12.

"Combinations of genetic changes in the human cAMP-responsive element modulator gene: a clue towards understanding some forms of male infertility?"
Vouk K. , Hudler P. , Strmsnik L. , Fink M. , Majdic G. , Zorn B. , Lalli E. , Sassone-Corsi P. , Debeljak N. , Komel R. , Rozman D.
Mol. Hum. Reprod.11:567-574(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 262-361;TISSUE SPECIFICITY
13.

"Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis."
Pati D. , Meistrich M.L. , Plon S.E.
Mol. Cell. Biol.19:5001-5013(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CDC34;UBIQUITINATION
14.

"CREM activator and repressor isoforms in human testis: sequence variations and inaccurate splicing during impaired spermatogenesis."
Behr R. , Weinbauer G.F.
Mol. Hum. Reprod.6:967-972(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS 2; 4; 13; 15; 17 AND 18);TISSUE SPECIFICITY
15.

"Different CREM-isoform gene expression between equine and human normal and impaired spermatogenesis."
Bloecher S. , Behr R. , Weinbauer G.F. , Bergmann M. , Steger K.
Theriogenology60:1357-1369(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS 5; 12; 14; 16 AND 19);TISSUE SPECIFICITY
16.

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-287; SER-290 AND SER-293;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
17.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-287 AND SER-293;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
18.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.

Product Feedback Wall

* Email:
*Comments: